Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | FABP7 | O15540 | 1/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7261536 | 0.96 | ALDH1A1 (0.56) | ALDH1A1KDM4EHSD17B10TSHRFABP7 | |
| SCHEMBL21886493 | 0.92 | ALDH1A1 (0.52) | ALDH1A1KDM4EHSD17B10TSHRFABP7 | |
| SCHEMBL26048629 | 0.92 | ALDH1A1 (0.52) | ALDH1A1KDM4EHSD17B10TSHRFABP7 | |
| SCHEMBL19830987 | 0.88 | TSHR (0.49) | ALDH1A1TSHRFABP7FABP5NPSR1 | |
| SCHEMBL28117364 | 0.82 | TSHR (0.47) | ALDH1A1TSHRFABP7FABP5NPSR1 | |
| Benzylamine SCHEMBL28176561 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRCYP1A2LMNA | |
| Benzylamine SCHEMBL28177489 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRCYP1A2LMNA | |
| Benzylamine SCHEMBL28176559 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRCYP1A2LMNA | |
| SCHEMBL24175315 | 0.80 | TSHR (0.45) | ALDH1A1TSHRFABP7FABP5CYP1A2 | |
| SCHEMBL29433900 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TSHRFABP7FABP5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536329-A4 | R(+)-TERAZOSIN | — | 1993-05-19 | — | — | EP | disclosed |
| EP-0536329-A1 | R(+)-TERAZOSIN. | ABBOTT LAB (US) | 1993-04-14 | — | — | EP | disclosed |