Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 6/20 | 0.48 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202439 | 0.86 | SOAT1 (0.63) | SOAT1ACAT1PTGS1PTGS2ALDH1A1 | |
| SCHEMBL9524785 | 0.80 | SOAT1 (0.74) | SOAT1ACAT1 | |
| SCHEMBL9525341 | 0.79 | SOAT1 (0.47) | SOAT1ACAT1NPY5R | |
| SCHEMBL9670092 | 0.71 | HPGD (0.56) | PTGS1PTGS2ALDH1A1HPGD | |
| SCHEMBL9214087 | 0.69 | PTGS1 (0.50) | PTGS1PTGS2ALDH1A1HPGD | |
| SCHEMBL9526283 | 0.66 | SOAT1 (0.78) | SOAT1ACAT1 | |
| SCHEMBL3379092 | 0.64 | SOAT1 (1.00) | SOAT1ACAT1 | |
| SCHEMBL9201449 | 0.64 | SOAT1 (1.00) | SOAT1ACAT1 | |
| Hydrochloric Acid SCHEMBL9212683 | 0.64 | SOAT1 (0.98) | SOAT1ACAT1 | |
| SCHEMBL9213110 | 0.63 | SOAT1 (0.98) | SOAT1ACAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993001184-A1 | IMIDAZOLES INHIBITORS AS ACAT AND THROMBOXANE TXA2 | RHONE-POULENC RORER LIMITED (GB) | 1993-01-21 | — | — | WO | claimed |
| EP-0522887-A1 | Imidazoles as ACAT- and thromboxane TxA2 inhibitors | RHONE-POULENC RORER LIMITED (GB) | 1993-01-13 | — | — | EP | claimed |
| WO-1993001184-A1 | IMIDAZOLES INHIBITORS AS ACAT AND THROMBOXANE TXA2 | RHONE-POULENC RORER LIMITED (GB) | 1993-01-21 | — | — | WO | disclosed |
| EP-0522887-A1 | Imidazoles as ACAT- and thromboxane TxA2 inhibitors | RHONE-POULENC RORER LIMITED (GB) | 1993-01-13 | — | — | EP | disclosed |