Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 6/20 | 0.47 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 10/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3378259 | 0.86 | SOAT1 (0.63) | SOAT1ACAT1 | |
| SCHEMBL29972770 | 0.86 | SOAT1 (0.63) | SOAT1ACAT1 | |
| SCHEMBL9565792 | 0.86 | SOAT1 (0.63) | SOAT1ACAT1 | |
| SCHEMBL9597124 | 0.81 | SOAT1 (0.48) | SOAT1ACAT1 | |
| SCHEMBL9524785 | 0.80 | SOAT1 (0.74) | SOAT1ACAT1 | |
| SCHEMBL9525449 | 0.79 | SOAT1 (0.48) | SOAT1ACAT1NPY5R | |
| SCHEMBL7640471 | 0.72 | KDM4E (0.36) | SOAT1ACAT1 | |
| SCHEMBL7640468 | 0.72 | KDM4E (0.36) | SOAT1ACAT1 | |
| SCHEMBL9214975 | 0.70 | SOAT1 (0.33) | SOAT1ACAT1 | |
| SCHEMBL9214981 | 0.68 | SOAT1 (0.33) | SOAT1ACAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993001184-A1 | IMIDAZOLES INHIBITORS AS ACAT AND THROMBOXANE TXA2 | RHONE-POULENC RORER LIMITED (GB) | 1993-01-21 | — | — | WO | claimed |
| EP-0522887-A1 | Imidazoles as ACAT- and thromboxane TxA2 inhibitors | RHONE-POULENC RORER LIMITED (GB) | 1993-01-13 | — | — | EP | claimed |
| WO-1993001184-A1 | IMIDAZOLES INHIBITORS AS ACAT AND THROMBOXANE TXA2 | RHONE-POULENC RORER LIMITED (GB) | 1993-01-21 | — | — | WO | disclosed |
| EP-0522887-A1 | Imidazoles as ACAT- and thromboxane TxA2 inhibitors | RHONE-POULENC RORER LIMITED (GB) | 1993-01-13 | — | — | EP | disclosed |