Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662074 | 0.89 | KMT2A (0.45) | KMT2AL3MBTL1POLBHCAR2KDM4E | |
| SCHEMBL2570620 | 0.85 | KMT2A (0.55) | KMT2AL3MBTL1POLBHCAR2KDM4E | |
| SCHEMBL10874128 | 0.83 | POLB (0.49) | KMT2AL3MBTL1POLBHCAR2KDM4E | |
| SCHEMBL14754870 | 0.83 | KMT2A (0.45) | KMT2AL3MBTL1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL17297343 | 0.83 | HCAR2 (0.51) | KMT2AHCAR2KDM4EMAPTCYP2C19 | |
| SCHEMBL10875034 | 0.82 | POLB (0.47) | KMT2AL3MBTL1POLBHCAR2KDM4E | |
| SCHEMBL10876901 | 0.81 | HCAR2 (0.50) | KMT2AHCAR2KDM4EMAPT | |
| SCHEMBL1516680 | 0.80 | HTT (0.66) | KMT2AL3MBTL1POLBHCAR2KDM4E | |
| SCHEMBL9525018 | 0.80 | POLB (0.45) | KMT2AL3MBTL1POLBHCAR2KDM4E | |
| SCHEMBL19156384 | 0.79 | TLR9 (0.41) | KMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0301751-A1 | Pyridinium derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |
| EP-0198311-A2 | Nicotin amides and their use as fungicidal agents | F. HOFFMANN-LA ROCHE AG (CH) | 1986-10-22 | — | — | EP | disclosed |