Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525298 | 0.87 | MAPT (0.51) | POLBMAPTKMT2AMAPK1KDM4E | |
| Hydrochloric Acid SCHEMBL9525965 | 0.84 | KDM4E (0.39) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL9525184 | 0.84 | MAPT (0.51) | MAPTKMT2AMAPK1KDM4EMEN1 | |
| SCHEMBL9528120 | 0.83 | MEN1 (0.52) | MAPTKMT2AMAPK1KDM4EMEN1 | |
| SCHEMBL9525837 | 0.82 | MAPT (0.48) | MAPTKMT2AMAPK1KDM4EMEN1 | |
| SCHEMBL9525714 | 0.81 | MEN1 (0.57) | POLBMAPTKMT2AMAPK1KDM4E | |
| SCHEMBL9524234 | 0.80 | MEN1 (0.58) | MAPTKMT2AMAPK1KDM4EMEN1 | |
| SCHEMBL9525482 | 0.79 | MEN1 (0.55) | POLBMAPTKMT2AMAPK1KDM4E | |
| SCHEMBL9525531 | 0.78 | MAPT (0.52) | MAPTKMT2AMAPK1KDM4EMEN1 | |
| SCHEMBL9525186 | 0.78 | MEN1 (0.53) | POLBMAPTKMT2AMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |