Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 13/20 | 0.47 |
| ▸ | MEN1 | O00255 | 8/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 11/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 9/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524488 | 0.84 | KDM4E (0.62) | KMT2AMEN1GAAKDM4EMAPT | |
| SCHEMBL9524479 | 0.84 | KDM4E (0.62) | KMT2AMEN1GAAKDM4EMAPT | |
| SCHEMBL9524504 | 0.83 | KMT2A (0.55) | KMT2AMEN1GAAKDM4EMAPT | |
| SCHEMBL3167850 | 0.80 | KMT2A (0.72) | KMT2AMEN1GAAKDM4EMAPT | |
| SCHEMBL420540 | 0.80 | KMT2A (0.72) | KMT2AMEN1GAAKDM4EMAPT | |
| SCHEMBL9524224 | 0.79 | KMT2A (0.60) | KMT2AMEN1GAAKDM4EMAPT | |
| SCHEMBL9524221 | 0.79 | KMT2A (0.60) | KMT2AMEN1GAAKDM4EMAPT | |
| SCHEMBL9525914 | 0.79 | CA1 (0.53) | KMT2AMEN1GAAKDM4EMAPT | |
| SCHEMBL9525542 | 0.76 | KMT2A (0.64) | KMT2AMEN1KDM4EMAPTMAPK1 | |
| SCHEMBL5463701 | 0.74 | KMT2A (0.48) | KMT2AMEN1GAAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274642-B1 | HERBICIDAL AND FUNGICIDAL AGENTS BASED ON SUBSTITUTED PYRAZOLIN-5-ONE DERIVATIVES | BAYER AG (DE) | 1993-08-11 | — | — | EP | claimed |
| EP-0274642-B1 | HERBICIDAL AND FUNGICIDAL AGENTS BASED ON SUBSTITUTED PYRAZOLIN-5-ONE DERIVATIVES | BAYER AG (DE) | 1993-08-11 | — | — | EP | disclosed |