Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | AMY1A | P0DUB6 | 13/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524224 | 0.91 | KMT2A (0.60) | KMT2AL3MBTL1MEN1KDM4EALDH1A1 | |
| SCHEMBL9524221 | 0.91 | KMT2A (0.60) | KMT2AL3MBTL1MEN1KDM4EALDH1A1 | |
| SCHEMBL9524488 | 0.90 | KDM4E (0.62) | KMT2AL3MBTL1MEN1KDM4EALDH1A1 | |
| SCHEMBL9524479 | 0.90 | KDM4E (0.62) | KMT2AL3MBTL1MEN1KDM4EALDH1A1 | |
| SCHEMBL9524504 | 0.87 | KMT2A (0.55) | KMT2AL3MBTL1MEN1KDM4EALDH1A1 | |
| SCHEMBL9818009 | 0.87 | AMY1A (0.58) | KMT2AL3MBTL1MEN1AMY1AALDH1A1 | |
| SCHEMBL9525818 | 0.84 | MEN1 (0.55) | KMT2AL3MBTL1MEN1AMY1AKDM4E | |
| SCHEMBL6951498 | 0.83 | L3MBTL1 (0.54) | KMT2AL3MBTL1MEN1AMY1AKDM4E | |
| SCHEMBL6951495 | 0.83 | L3MBTL1 (0.54) | KMT2AL3MBTL1MEN1AMY1AKDM4E | |
| SCHEMBL11244851 | 0.82 | AMY1A (0.59) | KMT2AL3MBTL1MEN1AMY1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274642-B1 | HERBICIDAL AND FUNGICIDAL AGENTS BASED ON SUBSTITUTED PYRAZOLIN-5-ONE DERIVATIVES | BAYER AG (DE) | 1993-08-11 | — | — | EP | claimed |
| US-5162528-A | Pre- and post-emergence; phytaphthora in tomato plants; rice and wheat | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-10 | — | — | US | claimed |
| EP-0274642-B1 | HERBICIDAL AND FUNGICIDAL AGENTS BASED ON SUBSTITUTED PYRAZOLIN-5-ONE DERIVATIVES | BAYER AG (DE) | 1993-08-11 | — | — | EP | disclosed |
| US-5162528-A | Pre- and post-emergence; phytaphthora in tomato plants; rice and wheat | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-10 | — | — | US | disclosed |
| US-5028717-A | Herbicidal and fungicidal agents based on substituted pyrazolin-5-one derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |
| US-4909827-A | Containing a C6-10 aryl group substituted in position 1 | BAYER AKTIENGESELLSCHAFT (DE) | 1990-03-20 | — | — | US | disclosed |
| EP-0274642-A2 | Herbicidal and fungicidal agents based on substituted pyrazolin-5-one derivatives | BAYER AG (DE) | 1988-07-20 | — | — | EP | disclosed |
| EP-0036387-B1 | PROCESS FOR THE PREPARATION OF HYDRAZONO-ISOINDOLINES | CIBA-GEIGY AG (CH) | 1986-01-22 | — | — | EP | disclosed |
| US-4460768-A | Nickel complex pigments of azines | CIBA-GEIGY CORPORATION (US) | 1984-07-17 | — | — | US | disclosed |
| US-4414395-A | REACTING AN IMINOISOINDOLE WITH HYDRAZINE | CIBA-GEIGY CORPORATION (US) | 1983-11-08 | — | — | US | disclosed |
| EP-0020299-B1 | NICKEL COMPLEXES OF AZINES, THEIR PREPARATION PROCESS, PIGMENTING PROCESS FOR A HIGH MOLECULAR ORGANIC MATERIAL AND THE MATERIAL SO OBTAINED | CIBA-GEIGY AG (CH) | 1983-02-09 | — | — | EP | disclosed |
| US-4355159-A | Nickel complex pigments of azines | CIBA-GEIGY CORPORATION (US) | 1982-10-19 | — | — | US | disclosed |
| EP-0036387-A2 | Process for the preparation of hydrazono-isoindolines | CIBA-GEIGY AG (CH) | 1981-09-23 | — | — | EP | disclosed |
| EP-0020299-A1 | Nickel complexes of azines, their preparation process, pigmenting process for a high molecular organic material and the material so obtained | CIBA-GEIGY AG (CH) | 1980-12-10 | — | — | EP | disclosed |