Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9469880 | 1.00 | CCKBR (0.62) | CCKBRCCKAR | |
| SCHEMBL8682574 | 0.89 | CCKBR (0.57) | CCKBRCCKAR | |
| SCHEMBL8682571 | 0.89 | CCKBR (0.57) | CCKBRCCKAR | |
| SCHEMBL7094959 | 0.89 | CCKBR (0.57) | CCKBRCCKAR | |
| SCHEMBL11961521 | 0.89 | BRD4 (0.55) | CCKBRCCKAR | |
| SCHEMBL8536342 | 0.89 | CCKBR (0.72) | CCKBRCCKAR | |
| SCHEMBL8536344 | 0.89 | CCKBR (0.72) | CCKBRCCKAR | |
| SCHEMBL4424632 | 0.80 | CCKBR (0.61) | CCKBRCCKAR | |
| SCHEMBL8683515 | 0.79 | EPHX1 (0.44) | CCKBR | |
| SCHEMBL11981798 | 0.79 | CCKBR (0.49) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0167919-B1 | BENZODIAZEPINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1993-05-05 | — | — | EP | claimed |
| EP-0167919-B1 | BENZODIAZEPINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1993-05-05 | — | — | EP | disclosed |
| US-5004741-A | Cholecystokinin(CCK); Treating Disorders Of The Gastrointestinal Tract, Central Nervous System And Of The Appetite Of Animals | MERCK & CO., INC. (US) | 1991-04-02 | — | — | US | disclosed |
| US-4820834-A | Benzodiazepine analogs | MERCK & CO., INC. (US) | 1989-04-11 | — | — | US | disclosed |
| EP-0284256-A1 | Benzodiazepine analogs | MERCK & CO. INC. (US) | 1988-09-28 | — | — | EP | disclosed |
| EP-0167919-A2 | Benzodiazepine derivatives and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1986-01-15 | — | — | EP | disclosed |