Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 6/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525971 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9525994 | 0.91 | ALDH1A1 (0.47) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9525990 | 0.91 | ALDH1A1 (0.47) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9524667 | 0.89 | KDM4E (0.57) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9524661 | 0.89 | KDM4E (0.57) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9526260 | 0.86 | KDM4E (0.51) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9526250 | 0.86 | KDM4E (0.51) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9525815 | 0.79 | KDM4E (0.48) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9525827 | 0.79 | KDM4E (0.48) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9525457 | 0.78 | KDM4E (0.46) | KDM4EALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |