SCHEMBL9526032

SCHEMBL9526032

CCc1ccnc2c1ccc1cccnc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 5/20 0.62
CCR8 P51685 5/20 0.62
L3MBTL1 Q9Y468 5/20 0.62
CCR5 P51681 3/20 0.62
MAPT P10636 5/20 0.55
KDM4E B2RXH2 4/20 0.55
LMNA P02545 4/20 0.55
TDP1 Q9NUW8 3/20 0.55
HTT P42858 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
HSP90AA1 P07900 2/20 0.55
GMNN O75496 1/20 0.55
TP53 P04637 1/20 0.55
MMP2 P08253 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2D6 P10635 1/20 0.55
MMP9 P14780 1/20 0.55
ALOX15 P16050 1/20 0.55
TSHR P16473 1/20 0.55
NFKB1 P19838 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7565615 0.85 CCR1 (0.50) CCR1CCR8L3MBTL1CCR5MAPT
SCHEMBL31026574 0.84 CCR1 (0.55) CCR1CCR8L3MBTL1CCR5MAPT
SCHEMBL22824073 0.83 L3MBTL1 (0.57) CCR1CCR8L3MBTL1CCR5MAPT
SCHEMBL4836883 0.83 CCR1 (0.57) CCR1CCR8L3MBTL1CCR5MAPT
SCHEMBL28412542 0.83 KDM4E (0.57) CCR1CCR8L3MBTL1CCR5MAPT
SCHEMBL23979275 0.82 CCR1 (0.57) CCR1CCR8L3MBTL1CCR5MAPT
SCHEMBL31026583 0.82 CCR1 (0.53) CCR1CCR8L3MBTL1CCR5MAPT
SCHEMBL31026584 0.82 CCR1 (0.53) CCR1CCR8L3MBTL1CCR5MAPT
SCHEMBL9295183 0.82 CCR1 (0.53) CCR1CCR8L3MBTL1CCR5MAPT
SCHEMBL14018705 0.81 CCR1 (0.48) CCR1CCR8L3MBTL1CCR5MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017011531-A2 ORGANIC LIGHT-EMITTING DIODE MATERIALS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2017-01-19 WO disclosed
EP-0227162-B1 COMPLEX-FORMING POLYMERS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-09-22 EP disclosed
US-5049672-A PURIFICATION, SEPARATION, CATALYSTS SHELL OIL COMPANY (US) 1991-09-17 US disclosed
US-4933455-A Lithiated bipyridyl compounds SHELL OIL COMPANY (US) 1990-06-12 US disclosed
US-4910264-A Monovinyl aromatic compound and complex forming moiety containing pyridine or phenanthroline ring SHELL OIL COMPANY (US) 1990-03-20 US disclosed
US-4873212-A Nitrogen-containing bidentate compound immobilized on a solid inorganic carrier SHELL OIL COMPANY (US) 1989-10-10 US disclosed
US-4873333-A Nitrogen-containing bidentate compound immobilized on a solid inorganic carrier SHELL OIL COMPANY (US) 1989-10-10 US disclosed
US-4814457-A 2,2*-BIPYRIDINE OR 1-10-PHENANTROLINE COMPOUNDS SHELL OIL COMPANY (US) 1989-03-21 US disclosed
EP-0227162-A2 Complex-forming polymers SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-07-01 EP disclosed