Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526051 | 0.88 | MEN1 (0.44) | HSD17B10POLBTSHRNPSR1KDR | |
| Hydrochloric Acid SCHEMBL9524176 | 0.82 | ALDH1A1 (0.42) | NPC1RAB9AALDH1A1HPGDLMNA | |
| Iodide SCHEMBL9525399 | 0.82 | ALDH1A1 (0.42) | NPC1RAB9AALDH1A1HPGDLMNA | |
| SCHEMBL9524021 | 0.81 | MEN1 (0.44) | HSD17B10POLBTSHRNPSR1KDR | |
| SCHEMBL9526046 | 0.80 | ALDH1A1 (0.42) | HSD17B10POLBTSHRNPSR1KDR | |
| SCHEMBL9524189 | 0.79 | MEN1 (0.49) | HSD17B10POLBTSHRNPSR1KDR | |
| SCHEMBL9524974 | 0.78 | ALDH1A1 (0.41) | HSD17B10POLBTSHRNPSR1KDR | |
| SCHEMBL10587025 | 0.78 | ALDH1A1 (0.42) | POLBALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL9525983 | 0.78 | NPC1 (0.46) | HSD17B10POLBTSHRNPSR1KDR | |
| SCHEMBL9526506 | 0.78 | NPC1 (0.44) | HSD17B10POLBTSHRNPSR1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |