Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 4/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | ALB | P02768 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21272204 | 1.00 | CCKBR (1.00) | CCKBRCHRM1MEN1LMNAALB | |
| SCHEMBL11822552 | 1.00 | CCKBR (1.00) | CCKBRCHRM1MEN1LMNAALB | |
| SCHEMBL21272084 | 0.87 | CHRM1 (1.00) | CCKBRCHRM1MEN1LMNAALB | |
| SCHEMBL21272085 | 0.87 | CHRM1 (1.00) | CCKBRCHRM1MEN1LMNAALB | |
| SCHEMBL21272212 | 0.87 | CCKBR (0.77) | CCKBRCHRM1MEN1LMNAALB | |
| SCHEMBL21272207 | 0.87 | CCKBR (0.77) | CCKBRCHRM1MEN1LMNAALB | |
| SCHEMBL21272087 | 0.86 | CCKBR (0.75) | CCKBRCHRM1 | |
| SCHEMBL21272090 | 0.86 | CCKBR (0.75) | CCKBRCHRM1 | |
| SCHEMBL21272180 | 0.85 | CHRM1 (0.77) | CCKBRCHRM1MEN1LMNAALB | |
| SCHEMBL21272182 | 0.85 | CHRM1 (0.77) | CCKBRCHRM1MEN1LMNAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0167919-B1 | BENZODIAZEPINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1993-05-05 | — | — | EP | disclosed |
| US-5004741-A | Cholecystokinin(CCK); Treating Disorders Of The Gastrointestinal Tract, Central Nervous System And Of The Appetite Of Animals | MERCK & CO., INC. (US) | 1991-04-02 | — | — | US | disclosed |
| US-4820834-A | Benzodiazepine analogs | MERCK & CO., INC. (US) | 1989-04-11 | — | — | US | disclosed |
| EP-0284256-A1 | Benzodiazepine analogs | MERCK & CO. INC. (US) | 1988-09-28 | — | — | EP | disclosed |
| EP-0167919-A2 | Benzodiazepine derivatives and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1986-01-15 | — | — | EP | disclosed |