Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9009328 | 0.90 | LMNA (0.38) | LMNACYP2C19HIF1AABCB1TDP1 | |
| SCHEMBL9009046 | 0.87 | LMNA (0.35) | LMNACYP2C19HIF1AABCB1TDP1 | |
| SCHEMBL9009307 | 0.87 | LMNA (0.43) | LMNACYP2C19HIF1AABCB1 | |
| SCHEMBL12871722 | 0.87 | LMNA (0.39) | LMNACYP2C19HIF1AABCB1 | |
| SCHEMBL9009212 | 0.85 | LMNA (0.50) | LMNACYP2C19HIF1AABCB1 | |
| SCHEMBL8905658 | 0.84 | LMNA (0.42) | LMNACYP2C19HIF1AABCB1TDP1 | |
| Malonic Acid SCHEMBL9760401 | 0.84 | LMNA (0.33) | LMNACYP2C19HIF1AABCB1 | |
| SCHEMBL8379840 | 0.83 | LMNA (0.39) | LMNACYP2C19HIF1AABCB1TDP1 | |
| SCHEMBL17124727 | 0.83 | LMNA (0.41) | LMNACYP2C19HIF1AABCB1TDP1 | |
| SCHEMBL8741511 | 0.82 | LMNA (0.39) | LMNACYP2C19HIF1AABCB1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308364-B1 | Dicarboxylic acid-bis(3,5-dicarbamoyl-2-4-6-triiodanilides), process for their preparation and X-ray contrast agents containing them | SCHERING AG (DE) | 1993-11-10 | — | — | EP | disclosed |
| EP-0308364-A2 | Dicarboxylic acid-bis(3,5-dicarbamoyl-2-4-6-triiodanilides), process for their preparation and X-ray contrast agents containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-03-22 | — | — | EP | disclosed |