Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BID | P55957 | 3/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.31 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.31 |
| ▸ | F7 | P08709 | 3/20 | 0.31 |
| ▸ | F3 | P13726 | 3/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ECE1 | P42892 | 1/20 | 0.31 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.31 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.31 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18244699 | 0.88 | SMYD2 (0.33) | CYP3A4HTTSMN1; SMN2SMYD2PPARG | |
| SCHEMBL18244698 | 0.88 | SMYD2 (0.33) | CYP3A4HTTSMN1; SMN2SMYD2PPARG | |
| SCHEMBL3705314 | 0.86 | SMYD2 (0.34) | CYP3A4HTTSMN1; SMN2SMYD2PPARG | |
| SCHEMBL9525137 | 0.85 | ELANE (0.34) | KDM4ECYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL9529914 | 0.85 | CYP4F2 (0.41) | KDM4EMAPTHSD17B10CYP3A4HTT | |
| SCHEMBL13778516 | 0.85 | SMYD2 (0.34) | MAPTCYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL9526961 | 0.85 | PTGER4 (0.31) | CYP3A4HTTSMN1; SMN2SMYD2PPARG | |
| SCHEMBL9526204 | 0.85 | SMYD2 (0.32) | CYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL9526923 | 0.85 | SMYD2 (0.32) | CYP3A4HTTSMN1; SMN2SMYD2 | |
| SCHEMBL9525868 | 0.84 | SMYD2 (0.34) | CYP3A4HTTSMN1; SMN2SMYD2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419610-B1 | NEW LEUKOTRIENE B4 DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-09-15 | — | — | EP | disclosed |