Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.30 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526923 | 0.88 | SMYD2 (0.32) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL9526204 | 0.88 | SMYD2 (0.32) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL20500283 | 0.87 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2PPARG | |
| SCHEMBL20500262 | 0.87 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2PPARG | |
| SCHEMBL4824010 | 0.87 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2PPARG | |
| SCHEMBL20500252 | 0.87 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2PPARG | |
| SCHEMBL4821411 | 0.87 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2PPARG | |
| SCHEMBL22664469 | 0.87 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2PPARG | |
| SCHEMBL4333525 | 0.87 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2PPARG | |
| SCHEMBL5073223 | 0.87 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419610-B1 | NEW LEUKOTRIENE B4 DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-09-15 | — | — | EP | disclosed |
| EP-0419610-A1 | NEW LEUKOTRIENE B4 DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR USE AS DRUGS. | SCHERING AG (DE) | 1991-04-03 | — | — | EP | disclosed |
| WO-1990011271-A1 | NEW LEUKOTRIENE B4 DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1990-10-04 | — | — | WO | disclosed |