Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 9/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ALB | P02768 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514683 | 1.00 | CCKBR (1.00) | CCKBRMEN1LMNAALBKMT2A | |
| Ether SCHEMBL9529454 | 0.94 | CCKBR (0.88) | CCKBR | |
| Ether SCHEMBL9526133 | 0.94 | CCKBR (0.88) | CCKBR | |
| SCHEMBL9525114 | 0.91 | CCKBR (0.84) | CCKBR | |
| SCHEMBL9526835 | 0.89 | CCKBR (0.81) | CCKBRLMNA | |
| SCHEMBL9866963 | 0.89 | CCKBR (1.00) | CCKBR | |
| SCHEMBL9526199 | 0.89 | CCKBR (1.00) | CCKBR | |
| SCHEMBL9525672 | 0.84 | CCKBR (0.72) | CCKBRMEN1LMNAALBKMT2A | |
| SCHEMBL9525678 | 0.84 | CCKBR (0.72) | CCKBRMEN1LMNAALBKMT2A | |
| SCHEMBL5491330 | 0.83 | CCKBR (0.73) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0167919-B1 | BENZODIAZEPINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1993-05-05 | — | — | EP | disclosed |
| US-5004741-A | Cholecystokinin(CCK); Treating Disorders Of The Gastrointestinal Tract, Central Nervous System And Of The Appetite Of Animals | MERCK & CO., INC. (US) | 1991-04-02 | — | — | US | disclosed |
| US-4820834-A | Benzodiazepine analogs | MERCK & CO., INC. (US) | 1989-04-11 | — | — | US | disclosed |
| EP-0284256-A1 | Benzodiazepine analogs | MERCK & CO. INC. (US) | 1988-09-28 | — | — | EP | disclosed |
| EP-0167919-A2 | Benzodiazepine derivatives and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1986-01-15 | — | — | EP | disclosed |