Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.82 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.81 |
| ▸ | HTR2C | P28335 | 1/20 | 0.77 |
| ▸ | HTR2B | P41595 | 1/20 | 0.77 |
| ▸ | NQO2 | P16083 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29351431 | 0.90 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL5361538 | 0.90 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL9490858 | 0.90 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL9424883 | 0.89 | MTNR1A (0.80) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL9492236 | 0.89 | MTNR1A (0.80) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL5929467 | 0.89 | MTNR1A (0.87) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| SCHEMBL12487213 | 0.89 | MTNR1A (0.80) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| Hydrochloric Acid SCHEMBL9491830 | 0.88 | MTNR1A (0.78) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| Agomelatine SCHEMBL114476 | 0.87 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2CHTR2BNQO2 | |
| Agomelatine SCHEMBL1158495 | 0.87 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2CHTR2BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447285-B1 | NAPHTHALENE DERIVATIVES, PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1993-05-12 | — | — | EP | claimed |
| EP-0447285-A1 | Naphthalene derivatives, procedure for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1991-09-18 | — | — | EP | claimed |