Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1056093 | 0.83 | ALOX12 (0.65) | GAAALOX12MEN1MAPTKMT2A | |
| SCHEMBL11495698 | 0.82 | CYP2C9 (0.61) | GAAALOX12MEN1MAPTKMT2A | |
| SCHEMBL7409572 | 0.82 | PTPN7 (0.48) | GAAALOX12MEN1MAPTKMT2A | |
| SCHEMBL28422492 | 0.82 | ALOX12 (0.63) | GAAALOX12MEN1MAPTKMT2A | |
| Methane SCHEMBL9754014 | 0.82 | ALOX12 (0.63) | GAAALOX12MEN1MAPTKMT2A | |
| SCHEMBL22444396 | 0.82 | ALOX12 (0.63) | GAAALOX12MEN1MAPTKMT2A | |
| SCHEMBL9754125 | 0.82 | ALOX12 (0.63) | GAAALOX12MEN1MAPTKMT2A | |
| SCHEMBL14715270 | 0.78 | CA9 (0.56) | GAAMAPTALDH1A1CA1CA9 | |
| SCHEMBL28943699 | 0.78 | ALOX12 (0.43) | GAAALOX12MEN1MAPTKMT2A | |
| SCHEMBL8847588 | 0.76 | ALOX12 (0.74) | GAAALOX12MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515546-A4 | TRIAZOLE ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | — | 1993-05-12 | — | — | EP | disclosed |
| EP-0515546-A1 | TRIAZOLE ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO. INC. (US) | 1992-12-02 | — | — | EP | disclosed |