Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 14/20 | 0.72 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.63 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.63 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.63 |
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | RXRA | P19793 | 1/20 | 0.60 |
| ▸ | RXRB | P28702 | 1/20 | 0.60 |
| ▸ | RXRG | P48443 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667780 | 0.86 | PTGER1 (0.72) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL1638061 | 0.86 | MAOB (0.62) | PTGER1PTGER4PTGER3PTGER2MAOB | |
| SCHEMBL18495766 | 0.85 | MAOB (0.56) | PTGER1PTGER4PTGER3PTGER2MAOB | |
| Acetic Acid SCHEMBL5690407 | 0.84 | RXRA (0.72) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL5096132 | 0.84 | PTGER1 (1.00) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL1637811 | 0.80 | MAOB (0.54) | PTGER1PTGER4PTGER3PTGER2MAOB | |
| SCHEMBL5110014 | 0.80 | PTGER1 (0.74) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL27794248 | 0.78 | PTGER1 (0.66) | PTGER1PTGER4PTGER3PTGER2RXRA | |
| SCHEMBL5933469 | 0.78 | PTGER1 (0.82) | PTGER1RXRARXRBRXRGCYP2C9 | |
| SCHEMBL1449798 | 0.77 | MAPT (0.53) | PTGER1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |