Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malonic Acid SCHEMBL11135797 | 0.88 | LMNA (0.49) | LMNACYP2C19HIF1AEGFRSRC | |
| Malonic Acid SCHEMBL9761104 | 0.86 | LMNA (0.51) | LMNACYP2C19HIF1AEGFRSRC | |
| Malonic Acid SCHEMBL11131920 | 0.82 | LMNA (0.50) | LMNACYP2C19HIF1A | |
| Malonic Acid SCHEMBL9525027 | 0.81 | LMNA (0.47) | LMNACYP2C19HIF1AEGFRSRC | |
| Malonic Acid SCHEMBL9527869 | 0.81 | LMNA (0.51) | LMNACYP2C19HIF1AEGFRSRC | |
| Malonic Acid SCHEMBL9530109 | 0.80 | LMNA (0.67) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL15489157 | 0.78 | LMNA (0.70) | LMNACYP2C19HIF1AEGFRSRC | |
| Cadaverine Tartrate SCHEMBL9526178 | 0.78 | LMNA (0.46) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL3057502 | 0.78 | LMNA (0.63) | LMNACYP2C19HIF1AEGFRSRC | |
| Malonic Acid SCHEMBL9526080 | 0.77 | LMNA (0.55) | LMNACYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308364-B1 | Dicarboxylic acid-bis(3,5-dicarbamoyl-2-4-6-triiodanilides), process for their preparation and X-ray contrast agents containing them | SCHERING AG (DE) | 1993-11-10 | — | — | EP | claimed |