Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 12/20 | 0.55 |
| ▸ | CA2 | P00918 | 12/20 | 0.55 |
| ▸ | CA4 | P22748 | 12/20 | 0.55 |
| ▸ | CA6 | P23280 | 12/20 | 0.55 |
| ▸ | PARP1 | P09874 | 5/20 | 0.46 |
| ▸ | MPL | P40238 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946519 | 0.83 | CA1 (0.63) | CA1CA2CA4CA6PARP1 | |
| SCHEMBL11703717 | 0.76 | KDM4E (0.50) | MEN1KMT2A | |
| SCHEMBL9527759 | 0.74 | CA1 (0.60) | CA1CA2CA4CA6PARP1 | |
| SCHEMBL9526768 | 0.71 | CA1 (0.59) | CA1CA2CA4CA6PARP1 | |
| SCHEMBL9527483 | 0.70 | KMT2A (0.36) | MEN1KMT2A | |
| SCHEMBL29370925 | 0.68 | CA1 (1.00) | CA1CA2CA4CA6MEN1 | |
| SCHEMBL2298597 | 0.68 | CA1 (1.00) | CA1CA2CA4CA6MEN1 | |
| SCHEMBL3797212 | 0.64 | SMN1; SMN2 (0.49) | MEN1KMT2A | |
| SCHEMBL2296063 | 0.64 | CA1 (0.83) | CA1CA2CA4CA6PARP1 | |
| SCHEMBL2300747 | 0.64 | CA1 (1.00) | CA1CA2CA4CA6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185360-A | Antioxidants, free radical scavengers | UNIVERSITY OF BATH (GB) | 1993-02-09 | — | — | US | disclosed |
| EP-0404536-A1 | Indenoindole compounds I | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | EP | disclosed |
| WO-1990015800-A1 | INDENOINDOLE COMPOUNDS | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | WO | disclosed |