Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 13/20 | 0.59 |
| ▸ | CA2 | P00918 | 13/20 | 0.59 |
| ▸ | CA4 | P22748 | 13/20 | 0.59 |
| ▸ | CA6 | P23280 | 13/20 | 0.59 |
| ▸ | PARP1 | P09874 | 6/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527759 | 0.80 | CA1 (0.60) | CA1CA2CA4CA6PARP1 | |
| SCHEMBL8946519 | 0.76 | CA1 (0.63) | CA1CA2CA4CA6PARP1 | |
| SCHEMBL29370925 | 0.73 | CA1 (1.00) | CA1CA2CA4CA6 | |
| SCHEMBL2298597 | 0.73 | CA1 (1.00) | CA1CA2CA4CA6 | |
| SCHEMBL9231467 | 0.72 | KDM4E (0.58) | — | |
| SCHEMBL27585673 | 0.72 | RAB9A (0.60) | CA1CA2 | |
| SCHEMBL3876816 | 0.72 | KIF11 (0.57) | — | |
| SCHEMBL6079999 | 0.71 | PARP1 (0.85) | PARP1 | |
| SCHEMBL9527581 | 0.71 | CA1 (0.46) | CA1CA2CA4CA6PARP1 | |
| SCHEMBL9526694 | 0.71 | CA1 (0.55) | CA1CA2CA4CA6PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185360-A | Antioxidants, free radical scavengers | UNIVERSITY OF BATH (GB) | 1993-02-09 | — | — | US | claimed |
| EP-0404536-A1 | Indenoindole compounds I | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | EP | claimed |
| WO-1990015800-A1 | INDENOINDOLE COMPOUNDS | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | WO | claimed |
| US-5185360-A | Antioxidants, free radical scavengers | UNIVERSITY OF BATH (GB) | 1993-02-09 | — | — | US | disclosed |
| EP-0404536-A1 | Indenoindole compounds I | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | EP | disclosed |
| WO-1990015800-A1 | INDENOINDOLE COMPOUNDS | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | WO | disclosed |