Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.51 |
| ▸ | AGT | P01019 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526824 | 0.85 | AGTR1 (0.53) | AGTR1AGTR2AGT | |
| SCHEMBL9530532 | 0.85 | AGTR1 (0.51) | AGTR1AGTR2AGT | |
| SCHEMBL9427854 | 0.83 | AGTR1 (0.51) | AGTR1AGTR2AGT | |
| SCHEMBL7400468 | 0.79 | AGTR1 (0.64) | AGTR1AGTR2 | |
| SCHEMBL14855527 | 0.79 | AGTR1 (0.66) | AGTR1AGTR2AGT | |
| SCHEMBL7308543 | 0.78 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL7312368 | 0.78 | AGTR1 (0.63) | AGTR1AGTR2AGT | |
| SCHEMBL9526126 | 0.78 | AGTR1 (0.54) | AGTR1AGTR2AGT | |
| SCHEMBL7303800 | 0.77 | AGTR1 (0.56) | AGTR1AGTR2AGT | |
| SCHEMBL7301221 | 0.77 | AGTR1 (0.64) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323841-B1 | SUBSTITUTED PYRROLE, PYRAZOLE AND TRIAZOLE ANGIOTENSIN II ANTAGONISTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-08-04 | — | — | EP | disclosed |