Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526609 | 0.97 | PLA2G4A (0.56) | PLA2G4AEPHX2PPARGCYSLTR1 | |
| SCHEMBL9528455 | 0.95 | EPHX2 (0.62) | PLA2G4AEPHX2PPARGCYSLTR1 | |
| SCHEMBL9527266 | 0.94 | PLA2G4A (0.57) | PLA2G4AEPHX2PPARGCYSLTR1 | |
| SCHEMBL9526909 | 0.92 | PLA2G4A (0.57) | PLA2G4AEPHX2PPARGCYSLTR1 | |
| SCHEMBL9528080 | 0.87 | PLA2G4A (0.56) | PLA2G4AEPHX2PPARGCYSLTR1 | |
| SCHEMBL9527970 | 0.87 | EPHX2 (0.65) | PLA2G4AEPHX2PPARGCYSLTR1 | |
| SCHEMBL9527273 | 0.85 | CYSLTR2 (0.52) | CYSLTR1 | |
| SCHEMBL9527709 | 0.84 | CYSLTR2 (0.59) | PLA2G4ACYSLTR1 | |
| SCHEMBL9877911 | 0.83 | — | — | |
| SCHEMBL9373246 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337767-B1 | CYCLIC AMIDES | ICI AMERICAS INC. (US) | 1993-01-13 | — | — | EP | claimed |
| US-5047402-A | Leukotriene Antagonists | ICI AMERICAS INC. (US) | 1991-09-10 | — | — | US | claimed |
| JP-2231485-A | — | — | None | — | — | JP | disclosed |
| EP-0337767-B1 | CYCLIC AMIDES | ICI AMERICAS INC. (US) | 1993-01-13 | — | — | EP | disclosed |
| US-5047402-A | Leukotriene Antagonists | ICI AMERICAS INC. (US) | 1991-09-10 | — | — | US | disclosed |
| JP-H02231485-A | CARBOCYCLIC AMIDE, PRODUCTION AND INTERMEDIATE THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AND FOR TREATING ALLERGIC AND INFLAMMATORY DISEASES | ICI AMERICAS INC | 1990-09-13 | — | — | JP | disclosed |
| EP-0337767-A1 | Cyclic amides | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | disclosed |