Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.76 |
| ▸ | HTR1A | P08908 | 1/20 | 0.76 |
| ▸ | DRD4 | P21917 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527937 | 0.95 | DRD2 (0.76) | DRD2HTR1ADRD4 | |
| SCHEMBL9492470 | 0.89 | DRD2 (0.71) | DRD2HTR1ADRD4 | |
| SCHEMBL20043775 | 0.89 | DRD2 (0.71) | DRD2HTR1ADRD4 | |
| SCHEMBL10663073 | 0.88 | DRD2 (0.72) | DRD2HTR1ADRD4 | |
| SCHEMBL9527393 | 0.87 | DRD2 (0.71) | DRD2HTR1ADRD4 | |
| SCHEMBL13534443 | 0.87 | DRD2 (0.71) | DRD2HTR1ADRD4 | |
| SCHEMBL17264052 | 0.87 | DRD2 (0.71) | DRD2HTR1ADRD4 | |
| SCHEMBL9528185 | 0.87 | DRD2 (0.71) | DRD2HTR1ADRD4 | |
| Tandospirone SCHEMBL22693814 | 0.86 | DRD2 (1.00) | DRD2HTR1ADRD4 | |
| Tandospirone SCHEMBL22381099 | 0.86 | DRD2 (1.00) | DRD2HTR1ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220873-B1 | Fused bicyclic imides with psychotropic activity | AMERICAN HOME PROD (US) | 1993-11-24 | — | — | EP | claimed |
| US-4957913-A | N-((4-ARYLPIPERAZINO)ALKYL) SUBSTITTUTED | AMERICAN HOME PRODUCTS CORP. (US) | 1990-09-18 | — | — | US | claimed |
| US-4892943-A | ANTIPSYCHOTIC, ANXIOLYTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-01-09 | — | — | US | claimed |
| EP-0220873-A1 | Fused bicyclic imides with psychotropic activity | AMERICAN HOME PRODUCTS CORPORATION (US) | 1987-05-06 | — | — | EP | claimed |
| US-4957913-A | N-((4-ARYLPIPERAZINO)ALKYL) SUBSTITTUTED | AMERICAN HOME PRODUCTS CORP. (US) | 1990-09-18 | — | — | US | disclosed |