Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | HCN1 | O60741 | 1/20 | 0.34 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30645250 | 0.89 | MME (0.40) | MMECETP | |
| SCHEMBL856751 | 0.89 | MME (0.40) | MMECETP | |
| SCHEMBL9527366 | 0.84 | ATM (0.42) | ATMSMN1; SMN2MME | |
| SCHEMBL9526683 | 0.83 | ATM (0.41) | ATMSMN1; SMN2MME | |
| SCHEMBL9527330 | 0.82 | TACR1 (0.40) | ATMSMN1; SMN2MMEHCN1HCN4 | |
| SCHEMBL9527850 | 0.81 | ATM (0.40) | ATMSMN1; SMN2MMEGHSRCETP | |
| Hydrochloric Acid SCHEMBL9527859 | 0.81 | ATM (0.40) | ATMSMN1; SMN2MME | |
| SCHEMBL9525675 | 0.76 | ALDH1A1 (0.36) | ATMSMN1; SMN2HCN1HCN4 | |
| SCHEMBL27796327 | 0.75 | MME (0.41) | SMN1; SMN2MMECETP | |
| SCHEMBL855127 | 0.73 | MME (0.42) | SMN1; SMN2MMECETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310745-B1 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | ORION-YHTYMÄ OY (FI) | 1993-01-27 | — | — | EP | disclosed |
| EP-0183492-B1 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos-Yhtyma Oy (FI) | 1989-11-15 | — | — | EP | disclosed |
| EP-0310745-A2 | Substituted imidazole derivatives and their preparation and use | ORION-YHTYMÄ OY (FI) | 1989-04-12 | — | — | EP | disclosed |
| US-4689339-A | 4-dihydroinden-2-yl-, 4-tetrahydronaphth-2-yl-, and 4-dihydrobenzofuran-2-ylimidazoles, useful to block α2 -adrenergic receptors | FARMOS YHTYMA OY (FI) | 1987-08-25 | — | — | US | disclosed |
| EP-0183492-A1 | Substituted imidazole derivatives and their preparation and use | Farmos-Yhtyma Oy (FI) | 1986-06-04 | — | — | EP | disclosed |