Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527770 | 1.00 | NOS3 (0.40) | NOS3NOS1NAMPTEPHX1MAOA | |
| SCHEMBL10452541 | 1.00 | NOS3 (0.40) | NOS3NOS1NAMPTEPHX1MAOA | |
| SCHEMBL10452540 | 1.00 | NOS3 (0.40) | NOS3NOS1NAMPTEPHX1MAOA | |
| SCHEMBL10453680 | 0.83 | SMN1; SMN2 (0.44) | NOS3NOS1EPHX1NPC1RAB9A | |
| SCHEMBL10453682 | 0.83 | SMN1; SMN2 (0.44) | NOS3NOS1EPHX1NPC1RAB9A | |
| SCHEMBL10453673 | 0.83 | EPHX1 (0.50) | EPHX1NPC1KMT2AHTTTSHR | |
| SCHEMBL10453672 | 0.83 | EPHX1 (0.50) | EPHX1NPC1KMT2AHTTTSHR | |
| SCHEMBL10453853 | 0.81 | EPHX1 (0.52) | NOS3NOS1EPHX1MAOAMAOB | |
| SCHEMBL9528808 | 0.81 | EPHX1 (0.52) | NOS3NOS1EPHX1MAOAMAOB | |
| SCHEMBL9528814 | 0.81 | EPHX1 (0.52) | NOS3NOS1EPHX1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |