SCHEMBL9528115

SCHEMBL9528115

CCCN1CCC(Cc2ccc3c(c2)c(Cc2ccc(C(=O)OC)cc2OC)cn3CCC)C1S

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 6/20 0.52
CYSLTR1 Q9Y271 6/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9528148 0.93 CYSLTR2 (0.58) CYSLTR2CYSLTR1
SCHEMBL9528080 0.86 PLA2G4A (0.56) CYSLTR1
SCHEMBL9527465 0.84 CYSLTR2 (0.53) CYSLTR2CYSLTR1
SCHEMBL9527273 0.84 CYSLTR2 (0.52) CYSLTR2CYSLTR1
SCHEMBL9527741 0.83 CYSLTR2 (0.54) CYSLTR2CYSLTR1
SCHEMBL9527211 0.83 CYSLTR2 (0.52) CYSLTR2CYSLTR1
SCHEMBL9490135 0.80 CYSLTR2 (0.56) CYSLTR2CYSLTR1
SCHEMBL9490426 0.80 CYSLTR2 (0.54) CYSLTR2CYSLTR1
SCHEMBL9490424 0.79 CYSLTR2 (0.53) CYSLTR2CYSLTR1
SCHEMBL9374065 0.79 CYSLTR2 (0.55) CYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0337767-B1 CYCLIC AMIDES ICI AMERICAS INC. (US) 1993-01-13 EP disclosed
US-5047402-A Leukotriene Antagonists ICI AMERICAS INC. (US) 1991-09-10 US disclosed
EP-0337767-A1 Cyclic amides ICI AMERICAS INC. (US) 1989-10-18 EP disclosed