Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896868 | 0.88 | NPY5R (0.50) | MAPTHTTLMNASMN1; SMN2NPC1 | |
| SCHEMBL9531721 | 0.87 | MAPT (0.44) | MAPTGRIN1GRIN2BHTTLMNA | |
| SCHEMBL21675987 | 0.82 | IDO1 (0.51) | MAPTGRIN1GRIN2BCA1CA2 | |
| SCHEMBL25873912 | 0.78 | GRIN1 (0.41) | MAPTGRIN1GRIN2BLMNATSHR | |
| SCHEMBL11318413 | 0.77 | SCN5A (0.44) | MAPTGRIN1GRIN2BHTTLMNA | |
| SCHEMBL11318408 | 0.77 | SCN5A (0.44) | MAPTGRIN1GRIN2BHTTLMNA | |
| SCHEMBL7898569 | 0.76 | NPY5R (0.47) | MAPTHTTLMNASMN1; SMN2NPC1 | |
| SCHEMBL17199018 | 0.75 | GAA (0.46) | MAPTGRIN1GRIN2BHTTCA1 | |
| SCHEMBL5391449 | 0.72 | HSD17B10 (0.45) | MAPTGRIN1GRIN2BLMNATSHR | |
| SCHEMBL5391446 | 0.72 | HSD17B10 (0.45) | MAPTGRIN1GRIN2BLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |