Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 6/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RNF4 | P78317 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528131 | 0.88 | MAPT (0.45) | KMT2AGAASMN1; SMN2LMNARECQL | |
| SCHEMBL7898569 | 0.88 | NPY5R (0.47) | NPY5RHDAC1MEN1KMT2APOLB | |
| SCHEMBL7019465 | 0.80 | NPY5R (0.49) | NPY5RHDAC1MEN1KMT2APOLB | |
| SCHEMBL9531721 | 0.80 | MAPT (0.44) | MEN1KMT2APOLBGAASMN1; SMN2 | |
| SCHEMBL8471745 | 0.75 | HPGD (0.49) | MEN1KMT2APOLBSMN1; SMN2LMNA | |
| SCHEMBL21675987 | 0.75 | IDO1 (0.51) | MEN1KMT2APOLBGAASMN1; SMN2 | |
| SCHEMBL11318408 | 0.73 | SCN5A (0.44) | GAASMN1; SMN2LMNARECQLNPC1 | |
| SCHEMBL11318413 | 0.73 | SCN5A (0.44) | GAASMN1; SMN2LMNARECQLNPC1 | |
| SCHEMBL25873912 | 0.71 | GRIN1 (0.41) | MEN1KMT2AGAASMN1; SMN2LMNA | |
| SCHEMBL17199018 | 0.69 | GAA (0.46) | MEN1KMT2AGAASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1148048-A2 | Polyaromatic antiviral compositions | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-24 | — | — | EP | disclosed |
| US-6147116-A | TOPICALLY ADMINISTERING BENZENE DERIVATIVE SUBSTITUTED WITH UREIDO-, THIOUREIDO, AND/OR SULFONAMIDO GROUPS TO TREAT HERPES | PHARMACIA & UPJOHN COMPANY (US) | 2000-11-14 | — | — | US | disclosed |
| US-5958983-A | NOVEL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST HERPES, TOPICAL ADMINISTRATION THEM TO TREAT PATIENTS WITH HERPES; WORK BY INHIBITING THE INITIATION OF HERPES VIRAL DNA SYNTHESIS IN HOST CELLS | PHARMACIA & UPJOHN COMPANY (US) | 1999-09-28 | — | — | US | disclosed |