Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528139 | 1.00 | MGAM (0.30) | MGAM | |
| SCHEMBL10541473 | 0.76 | POLB (0.39) | — | |
| SCHEMBL10741421 | 0.74 | — | — | |
| SCHEMBL7631477 | 0.73 | CTSV (0.31) | — | |
| SCHEMBL3337695 | 0.72 | — | — | |
| SCHEMBL3337690 | 0.72 | — | — | |
| SCHEMBL10573600 | 0.70 | GAA (0.38) | — | |
| SCHEMBL9782637 | 0.68 | — | — | |
| SCHEMBL9658208 | 0.67 | — | — | |
| SCHEMBL4098581 | 0.67 | BRD4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187500-B1 | MONOBACTAMS | THE UPJOHN COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |
| US-4883869-A | BACTERICIDES, ANTIBIOTICS | THE UPJOHN COMPANY (US) | 1989-11-28 | — | — | US | disclosed |
| US-4837318-A | Carbonate substituted monobactams as antibiotics | THE UPJOHN COMPANY (US) | 1989-06-06 | — | — | US | disclosed |
| EP-0221954-A1 | CARBONATE SUBSTITUTED MONOBACTAMS AS ANTIBIOTICS | THE UPJOHN COMPANY (US) | 1987-05-20 | — | — | EP | disclosed |
| WO-1986006722-A1 | CARBONATE SUBSTITUTED MONOBACTAMS AS ANTIBIOTICS | THE UPJOHN COMPANY (US) | 1986-11-20 | — | — | WO | disclosed |
| EP-0187500-A1 | Monobactams | THE UPJOHN COMPANY (US) | 1986-07-16 | — | — | EP | disclosed |