Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.52 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.52 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527588 | 0.95 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL9528110 | 0.93 | CYSLTR2 (0.52) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL9527890 | 0.92 | CYSLTR2 (0.51) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL9527925 | 0.90 | CYSLTR1 (0.46) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL9526601 | 0.89 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1PLA2G4ALTB4R | |
| SCHEMBL9877877 | 0.88 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1PLA2G4ALTB4R | |
| SCHEMBL9527769 | 0.86 | CYSLTR1 (0.44) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL9526810 | 0.85 | CYSLTR2 (0.51) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL9527465 | 0.83 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1 | |
| SCHEMBL9527489 | 0.83 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1PLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337767-B1 | CYCLIC AMIDES | ICI AMERICAS INC. (US) | 1993-01-13 | — | — | EP | disclosed |
| US-5047402-A | Leukotriene Antagonists | ICI AMERICAS INC. (US) | 1991-09-10 | — | — | US | disclosed |