Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.59 |
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.59 |
| ▸ | PLA2G4A | P47712 | 7/20 | 0.48 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527588 | 0.93 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL9528153 | 0.88 | CYSLTR2 (0.52) | CYSLTR2CYSLTR1PLA2G4ALTB4R | |
| SCHEMBL9527319 | 0.84 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1PLA2G4ALTB4R | |
| SCHEMBL9528110 | 0.83 | CYSLTR2 (0.52) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL9526810 | 0.83 | CYSLTR2 (0.51) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL9527890 | 0.82 | CYSLTR2 (0.51) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL9527475 | 0.82 | CYSLTR2 (0.58) | CYSLTR2CYSLTR1PLA2G4ALTB4R | |
| SCHEMBL9526681 | 0.80 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1PLA2G4ALTB4R | |
| SCHEMBL9526691 | 0.80 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1PLA2G4ALTB4R | |
| SCHEMBL9526782 | 0.79 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1PLA2G4ALTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047402-A | Leukotriene Antagonists | ICI AMERICAS INC. (US) | 1991-09-10 | — | — | US | disclosed |