SCHEMBL9528217

SCHEMBL9528217

Brc1ccc(CCNc2ccccc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.70
TAAR1 Q96RJ0 2/20 0.53
MAPT P10636 2/20 0.50
ALDH1A1 P00352 1/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
MGLL Q99685 1/20 0.49
F2 P00734 1/20 0.46
KCNH2 Q12809 1/20 0.46
GRIN2B Q13224 1/20 0.46
PLAAT3 P53816 1/20 0.46
PLAAT5 Q96KN8 1/20 0.46
PLAAT2 Q9NWW9 1/20 0.46
PLAAT4 Q9UL19 1/20 0.46
GPR84 Q9NQS5 1/20 0.45
SIGMAR1 Q99720 1/20 0.45
CCNC P24863 1/20 0.44
CDK8 P49336 1/20 0.44
HTR2A P28223 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL707113 0.92 L3MBTL1 (0.70) L3MBTL1TAAR1MAPTALDH1A1RAB9A
SCHEMBL10055000 0.89 L3MBTL1 (0.86) L3MBTL1TAAR1MAPTALDH1A1RAB9A
SCHEMBL24375975 0.85 L3MBTL1 (0.95) L3MBTL1TAAR1MAPTALDH1A1RAB9A
SCHEMBL21186859 0.85 L3MBTL1 (0.95) L3MBTL1TAAR1MAPTALDH1A1RAB9A
SCHEMBL88597 0.85 L3MBTL1 (0.95) L3MBTL1TAAR1MAPTALDH1A1RAB9A
Hydrochloric Acid SCHEMBL8746161 0.83 L3MBTL1 (1.00) L3MBTL1TAAR1MAPTALDH1A1RAB9A
SCHEMBL30266145 0.82 L3MBTL1 (0.73) L3MBTL1MAPTALDH1A1F2KCNH2
SCHEMBL2311052 0.82 L3MBTL1 (0.73) L3MBTL1TAAR1MAPTALDH1A1RAB9A
SCHEMBL5543154 0.81 TAAR1 (0.50) L3MBTL1TAAR1MAPTRAB9ASMN1; SMN2
SCHEMBL706218 0.81 L3MBTL1 (0.55) L3MBTL1MAPTALDH1A1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118546064-A Preparation method of aromatic alkylamine 贵州民族大学 2024-08-27 CN disclosed
EP-0573548-A1 NEUROPROTECTANT AGENTS. AMERICAN HOME PROD (US) 1993-12-15 EP disclosed
WO-1992014813-A1 NEUROPROTECTANT AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1992-09-03 WO disclosed