Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1426071 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL3789712 | 0.89 | GAA (0.40) | GAAMAPTDAOKCNA3KCNA5 | |
| SCHEMBL7100687 | 0.87 | DAO (0.43) | GAAMAPTDAOKCNA3KCNA5 | |
| SCHEMBL464768 | 0.82 | — | — | |
| SCHEMBL6114991 | 0.81 | TBXAS1 (0.47) | MAPTDAOLMNATLR8TLR7 | |
| SCHEMBL11440961 | 0.81 | TBXAS1 (0.47) | MAPTDAOLMNATLR8TLR7 | |
| SCHEMBL6114927 | 0.81 | TBXAS1 (0.47) | MAPTDAOLMNATLR8TLR7 | |
| SCHEMBL6114716 | 0.81 | TBXAS1 (0.47) | MAPTDAOLMNATLR8TLR7 | |
| SCHEMBL5691507 | 0.81 | TBXAS1 (0.47) | MAPTDAOLMNATLR8TLR7 | |
| SCHEMBL6114640 | 0.81 | TBXAS1 (0.47) | MAPTDAOLMNATLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993001184-A1 | IMIDAZOLES INHIBITORS AS ACAT AND THROMBOXANE TXA2 | RHONE-POULENC RORER LIMITED (GB) | 1993-01-21 | — | — | WO | disclosed |
| EP-0522887-A1 | Imidazoles as ACAT- and thromboxane TxA2 inhibitors | RHONE-POULENC RORER LIMITED (GB) | 1993-01-13 | — | — | EP | disclosed |