Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528543 | 1.00 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2CYP2C19ALDH1A1 | |
| SCHEMBL9528315 | 1.00 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2CYP2C19ALDH1A1 | |
| SCHEMBL9528535 | 1.00 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2CYP2C19ALDH1A1 | |
| SCHEMBL10453738 | 1.00 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2CYP2C19ALDH1A1 | |
| SCHEMBL10453737 | 1.00 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2CYP2C19ALDH1A1 | |
| SCHEMBL10453340 | 0.81 | TAS1R3 (0.39) | NPC1RAB9AEPHX1EPHX2MAPK1 | |
| SCHEMBL10773300 | 0.79 | GRM4 (0.40) | NPC1RAB9ASMN1; SMN2ALDH1A1EPHX1 | |
| SCHEMBL10773298 | 0.79 | GRM4 (0.40) | NPC1RAB9ASMN1; SMN2ALDH1A1EPHX1 | |
| SCHEMBL10453437 | 0.76 | AR (0.38) | NPC1RAB9ASMN1; SMN2CYP2C19ALDH1A1 | |
| SCHEMBL10453438 | 0.76 | AR (0.38) | NPC1RAB9ASMN1; SMN2CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |