SCHEMBL9528445

SCHEMBL9528445

CC(=O)CCCOC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15745405 0.91 PAOX (0.46)
SCHEMBL4406961 0.85
SCHEMBL26695774 0.84 ALDH1A1 (0.32)
SCHEMBL2183252 0.83
SCHEMBL15149728 0.80 MAPT (0.30)
SCHEMBL6720592 0.79
SCHEMBL2285951 0.78
SCHEMBL2288398 0.78
SCHEMBL2285947 0.78
SCHEMBL2288400 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230346696-A1 SPRAY DRIED LOW HYGROSCOPICITY ACTIVE POWDER COMPOSITIONS PHILIP MORRIS PRODUCTS S.A. (CH) 2023-11-02 US disclosed
US-20230301919-A1 FREEZE DRIED LOW HYGROSCOPICITY ACTIVE POWDER COMPOSITIONS PHILIP MORRIS PRODUCTS S.A. (CH) 2023-09-28 US disclosed
WO-2010112942-A1 NOVEL DICARBOXYLIC ACID LINKED AMINO ACID AND PEPTIDE PRODRUGS OF OPIOIDS AND USES THEREOF SHIRE LLC (US) 2010-10-07 WO disclosed
EP-0237522-B1 PHARMACEUTICALLY ACTIVE DERIVATIVES OF TRYPTOPHAN AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ROTTA RESEARCH LABORATORIUM S.P.A. (IT) 1993-02-24 EP disclosed
US-4870097-A ANALGESICS, CENTRAL NERVOUS SYSTEM DISORDERS ROTTA RESEARCH LABORATORIUM S.P.A. (IT) 1989-09-26 US disclosed
US-4791215-A DIGESTIVE SYSTEM DISORDERS ROTTA RESEARCH LABORATORIUM S.P.A. (IT) 1988-12-13 US disclosed
EP-0237522-A1 PHARMACEUTICALLY ACTIVE DERIVATIVES OF TRYPTOPHAN AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. ROTTA RESEARCH LAB (IT) 1987-09-23 EP disclosed
WO-1986003489-A1 PHARMACEUTICALLY ACTIVE DERIVATIVES OF TRYPTOPHAN AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ROTTA RESEARCH LABORATORIUM S.P.A. (IT) 1986-06-19 WO disclosed
US-4576951-A ANAGELSICS, NARCOTICS, ENKEPHALINS, POTENIATION ROTTA RESEARCH LABORATORIUM S.P.A. (IT) 1986-03-18 US disclosed