SCHEMBL9528544

SCHEMBL9528544

O=c1oc(-c2ccccc2NS(=O)(=O)c2ccc(-c3ccccc3)cc2)nc2ccccc12

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.86
MEN1 O00255 5/20 0.86
MAPT P10636 5/20 0.81
GAA P10253 2/20 0.81
ALDH1A1 P00352 1/20 0.81
LMNA P02545 2/20 0.76
ELANE P08246 1/20 0.53
C1R P00736 7/20 0.51
F2 P00734 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
PLG P00747 1/20 0.51
KLK1 P06870 1/20 0.51
PRSS1 P07477 1/20 0.51
C1S P09871 1/20 0.51
ATM Q13315 1/20 0.51
STK33 Q9BYT3 1/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
CA12 O43570 1/20 0.48
CA2 P00918 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10819490 0.99 KMT2A (0.88) KMT2AMEN1MAPTGAAALDH1A1
SCHEMBL5975597 0.93 KMT2A (1.00) KMT2AMEN1MAPTGAAALDH1A1
SCHEMBL5975754 0.90 KMT2A (0.84) KMT2AMEN1MAPTGAAALDH1A1
SCHEMBL9528246 0.90 MAPT (1.00) KMT2AMEN1MAPTGAAALDH1A1
SCHEMBL924320 0.90 MAPT (1.00) KMT2AMEN1MAPTGAAALDH1A1
SCHEMBL7185309 0.87 KMT2A (0.79) KMT2AMEN1MAPTGAAALDH1A1
SCHEMBL9527940 0.87 KMT2A (0.79) KMT2AMEN1MAPTGAAALDH1A1
SCHEMBL2314299 0.86 KMT2A (1.00) KMT2AMEN1MAPTGAAALDH1A1
SCHEMBL30183217 0.86 KMT2A (1.00) KMT2AMEN1MAPTGAAALDH1A1
SCHEMBL9530204 0.83 KMT2A (0.81) KMT2AMEN1MAPTGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0314350-B1 FLUORESCENT COMPOUNDS AND THEIR USE THOMAS DE LA RUE & COMPANY LIMITED (GB) 1993-10-06 EP claimed
EP-0314350-B1 FLUORESCENT COMPOUNDS AND THEIR USE THOMAS DE LA RUE & COMPANY LIMITED (GB) 1993-10-06 EP disclosed