Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528317 | 1.00 | KMT2A (0.45) | KMT2AMEN1TSHRGRM4ALDH1A1 | |
| SCHEMBL10453739 | 1.00 | KMT2A (0.45) | KMT2AMEN1TSHRGRM4ALDH1A1 | |
| SCHEMBL10773303 | 0.79 | MAP2K1 (0.47) | KMT2AMEN1GRM4ALDH1A1MAPT | |
| SCHEMBL10453341 | 0.78 | MEN1 (0.41) | KMT2AMEN1GRM4ALDH1A1MAPT | |
| SCHEMBL10453439 | 0.77 | IDO1 (0.45) | KMT2AMEN1TSHRALDH1A1MAPT | |
| SCHEMBL9529344 | 0.74 | EPHX1 (0.50) | KMT2AMEN1TSHRCXCR4MAPT | |
| SCHEMBL10453855 | 0.74 | EPHX1 (0.50) | KMT2AMEN1TSHRCXCR4MAPT | |
| SCHEMBL10453589 | 0.74 | EPHX1 (0.50) | KMT2AMEN1TSHRCXCR4MAPT | |
| SCHEMBL9528819 | 0.74 | EPHX1 (0.50) | KMT2AMEN1TSHRCXCR4MAPT | |
| SCHEMBL9533078 | 0.74 | KMT2A (0.42) | KMT2AMEN1ALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| US-4921939-A | GUANIDINE AND AMIDINE COMPOUNDS CONTAINING ACID GROUPS | UNIVERSITE CLAUDE BERNARD -LYON 1 (FR) | 1990-05-01 | — | — | US | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |