SCHEMBL9533078

SCHEMBL9533078

C/N=C(/Nc1cc(Cl)cc(Cl)c1)SC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.42
MEN1 O00255 4/20 0.42
MAPT P10636 3/20 0.42
NPSR1 Q6W5P4 2/20 0.42
RAB9A P51151 2/20 0.42
IDO1 P14902 1/20 0.40
MAOB P27338 1/20 0.40
HTR3E A5X5Y0 1/20 0.39
HTR3B O95264 1/20 0.39
HTR3A P46098 1/20 0.39
HTR3D Q70Z44 1/20 0.39
HTR3C Q8WXA8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
FABP4 P15090 1/20 0.38
P2RY1 P47900 1/20 0.36
POLB P06746 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
XBP1 P17861 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9533084 1.00 KMT2A (0.42) KMT2AMEN1MAPTNPSR1RAB9A
SCHEMBL10453732 0.81 HTR3E (0.42) KMT2AMEN1MAPTNPSR1RAB9A
SCHEMBL10453731 0.81 HTR3E (0.42) KMT2AMEN1MAPTNPSR1RAB9A
SCHEMBL15543683 0.79 MAPT (0.38) KMT2AMEN1MAPTNPSR1RAB9A
SCHEMBL15543685 0.79 MAPT (0.38) KMT2AMEN1MAPTNPSR1RAB9A
SCHEMBL10453739 0.74 KMT2A (0.45) KMT2AMEN1MAPTNPSR1RAB9A
SCHEMBL9528549 0.74 KMT2A (0.45) KMT2AMEN1MAPTNPSR1RAB9A
SCHEMBL9528317 0.74 KMT2A (0.45) KMT2AMEN1MAPTNPSR1RAB9A
SCHEMBL5391446 0.74 HSD17B10 (0.45) KMT2AMEN1MAPTRAB9APOLB
SCHEMBL5391449 0.74 HSD17B10 (0.45) KMT2AMEN1MAPTRAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0299533-B1 HIGH POTENCY SWEETENING AGENTS THE NUTRASWEET COMPANY (a Delaware corporation) (US) 1993-04-07 EP disclosed
WO-1989000563-A1 HIGH POTENCY SWEETENING AGENTS THE NUTRASWEET COMPANY (US) 1989-01-26 WO disclosed