Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL136258 | 0.86 | CYP1A2 (0.81) | LMNACYP1A2CYP2C19MAPTKMT2A | |
| SCHEMBL25699179 | 0.86 | CYP1A2 (0.74) | LMNACYP1A2CYP2C19MAPTHTT | |
| Terbuthylazine SCHEMBL671911 | 0.85 | KMT2A (0.60) | LMNACYP1A2CYP2C19MAPTKMT2A | |
| Terbuthylazine SCHEMBL9715175 | 0.85 | KMT2A (0.60) | LMNACYP1A2CYP2C19MAPTKMT2A | |
| SCHEMBL9528412 | 0.83 | LMNA (0.64) | LMNACYP1A2CYP2C19MAPTKMT2A | |
| SCHEMBL9789563 | 0.81 | KMT2A (0.53) | LMNACYP1A2CYP2C19KMT2AGAA | |
| SCHEMBL9789558 | 0.81 | KMT2A (0.53) | LMNACYP1A2CYP2C19KMT2AGAA | |
| SCHEMBL9789561 | 0.81 | KMT2A (0.53) | LMNACYP1A2CYP2C19KMT2AGAA | |
| Simazine SCHEMBL37774 | 0.81 | LMNA (1.00) | LMNACYP1A2CYP2C19MAPTKMT2A | |
| Simazine SCHEMBL8409822 | 0.81 | LMNA (1.00) | LMNACYP1A2CYP2C19MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355385-B1 | SUBSTITUTED 4-SULPHONYLAMINO-2-AZINYL-1,2,4-TRIAZOL-3-ONES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| US-5151514-A | Triazine substituted herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-29 | — | — | US | disclosed |
| US-5142060-A | Herbicidal substituted 4-sulphonylamino-2-azinyl-1,2,4-triazol-3-ones | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-25 | — | — | US | disclosed |
| US-5089627-A | Chemical intermediates therefor | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-5085687-A | HERBICIDAL SUBSTITUTED 4-SULPHONYLAMINO-2-AZINYL-1,2,4-TRIAZOL-3-ONES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-04 | — | — | US | disclosed |
| US-4988381-A | HERBICIDES, PLANT GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| EP-0355385-A1 | Substituted 4-sulphonylamino-2-azinyl-1,2,4-triazol-3-ones, process and intermediates for their preparation and their use as herbicides | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |