Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528256 | 0.93 | PLA2G4A (0.40) | CYSLTR1CYSLTR2PPARG | |
| SCHEMBL9528720 | 0.85 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2MAPTKMT2APDE4D | |
| SCHEMBL9531909 | 0.84 | CYSLTR1 (0.51) | CYSLTR1CYSLTR2MAPTKMT2APDE4D | |
| SCHEMBL9526857 | 0.84 | CYSLTR1 (0.44) | CYSLTR1CYSLTR2MAPTKMT2APDE4D | |
| SCHEMBL9527465 | 0.82 | CYSLTR2 (0.53) | CYSLTR1CYSLTR2 | |
| SCHEMBL9527741 | 0.77 | CYSLTR2 (0.54) | CYSLTR1CYSLTR2 | |
| SCHEMBL9526756 | 0.77 | PLA2G4A (0.48) | CYSLTR1CYSLTR2 | |
| SCHEMBL9490124 | 0.76 | MAPT (0.39) | TP53MAPTGLAKMT2A | |
| SCHEMBL9527659 | 0.75 | CYSLTR1 (0.44) | CYSLTR1CYSLTR2EPHX2PPARG | |
| SCHEMBL9491087 | 0.75 | PLA2G4A (0.35) | TP53MAPTGLAKMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337767-B1 | CYCLIC AMIDES | ICI AMERICAS INC. (US) | 1993-01-13 | — | — | EP | disclosed |
| US-5047402-A | Leukotriene Antagonists | ICI AMERICAS INC. (US) | 1991-09-10 | — | — | US | disclosed |
| EP-0337767-A1 | Cyclic amides | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | disclosed |