SCHEMBL95289

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5498009	0.87	RAB9A (0.71)	NPC1RAB9AALDH1A1GAAMAPT
	SCHEMBL2105853	0.84	NPC1 (0.67)	NPC1RAB9AALDH1A1GAAMAPT
	SCHEMBL12368157	0.83	NPC1 (0.65)	NPC1RAB9AALDH1A1GAAMAPT
	SCHEMBL1984206	0.82	RAB9A (0.65)	NPC1RAB9AALDH1A1GAAMAPT
	SCHEMBL94789	0.82	NPC1 (0.81)	NPC1RAB9AALDH1A1HTTSMN1; SMN2
	SCHEMBL95395	0.81	NR1H4 (0.68)	NPC1RAB9AALDH1A1MAPTHPGD
	SCHEMBL14082968	0.80	NPC1 (0.62)	NPC1RAB9AALDH1A1GAAMAPT
	SCHEMBL13202404	0.80	NPC1 (0.62)	NPC1RAB9AALDH1A1GAAMAPT
	SCHEMBL96330	0.79	MAPT (0.73)	NPC1RAB9AGAAMAPTTSHR
	SCHEMBL22025463	0.79	NPC1 (0.63)	NPC1RAB9AALDH1A1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.