Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.59 |
| ▸ | HRH1 | P35367 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HRH2 | P25021 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9528810 | 0.91 | HRH3 (0.71) | HRH3KCNH2HRH1HRH4LTA4H | |
| SCHEMBL9527901 | 0.90 | HRH3 (0.74) | HRH3KCNH2HRH1SMN1; SMN2LTA4H | |
| Hydrochloric Acid SCHEMBL9529620 | 0.89 | NPC1 (0.65) | HRH3KCNH2HRH1KDM4EALDH1A1 | |
| SCHEMBL9528301 | 0.86 | HRH3 (0.68) | HRH3KCNH2ALDH1A1MEN1KMT2A | |
| SCHEMBL9527128 | 0.86 | MEN1 (0.77) | HRH3ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9528330 | 0.85 | HRH3 (0.67) | HRH3ALDH1A1MEN1KMT2ALTA4H | |
| Hydrochloric Acid SCHEMBL9528262 | 0.85 | KMT2A (0.75) | HRH3ALDH1A1MEN1KMT2A | |
| SCHEMBL9530966 | 0.84 | HRH3 (0.76) | HRH3KDM4E | |
| SCHEMBL2823877 | 0.83 | HRH3 (0.87) | HRH3KCNH2HRH1KDM4EALDH1A1 | |
| SCHEMBL4084100 | 0.83 | HRH3 (0.87) | HRH3KCNH2HRH1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542846-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-05-26 | — | — | EP | claimed |