Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9528330 | 0.99 | HRH3 (0.67) | HRH3MEN1KMT2ALMNAHTT | |
| Hydrochloric Acid SCHEMBL9528258 | 0.87 | HRH3 (0.60) | HRH3MEN1KMT2ALMNAHTT | |
| SCHEMBL9527128 | 0.87 | MEN1 (0.77) | HRH3MEN1KMT2AALDH1A1PSMB1 | |
| SCHEMBL9529137 | 0.86 | HRH3 (0.63) | HRH3MEN1KMT2ALTA4HSLC6A4 | |
| SCHEMBL9527518 | 0.86 | LTA4H (0.61) | HRH3MEN1KMT2ALTA4HSLC6A4 | |
| Hydrochloric Acid SCHEMBL9528262 | 0.86 | KMT2A (0.75) | HRH3MEN1KMT2AALDH1A1PSMB1 | |
| SCHEMBL9530966 | 0.85 | HRH3 (0.76) | HRH3PSMB1PSMB5 | |
| SCHEMBL7434707 | 0.84 | HRH3 (0.88) | HRH3MEN1KMT2ALMNAHTT | |
| Hydrochloric Acid SCHEMBL9527233 | 0.84 | HRH3 (0.74) | HRH3PSMB1PSMB5 | |
| SCHEMBL27431539 | 0.84 | HRH3 (0.64) | HRH3MEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542846-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-05-26 | — | — | EP | claimed |