Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529338 | 0.82 | EPHX1 (0.52) | NOS3NOS1SMN1; SMN2HRH3EPHX2 | |
| SCHEMBL10453587 | 0.82 | EPHX1 (0.52) | NOS3NOS1SMN1; SMN2HRH3EPHX2 | |
| SCHEMBL9528808 | 0.82 | EPHX1 (0.52) | NOS3NOS1SMN1; SMN2HRH3EPHX2 | |
| SCHEMBL10453854 | 0.82 | EPHX1 (0.52) | NOS3NOS1SMN1; SMN2HRH3EPHX2 | |
| SCHEMBL9529332 | 0.82 | EPHX1 (0.52) | NOS3NOS1SMN1; SMN2HRH3EPHX2 | |
| SCHEMBL10453586 | 0.82 | EPHX1 (0.52) | NOS3NOS1SMN1; SMN2HRH3EPHX2 | |
| SCHEMBL10453853 | 0.82 | EPHX1 (0.52) | NOS3NOS1SMN1; SMN2HRH3EPHX2 | |
| SCHEMBL9528814 | 0.82 | EPHX1 (0.52) | NOS3NOS1SMN1; SMN2HRH3EPHX2 | |
| SCHEMBL9528123 | 0.80 | ALDH1A1 (0.50) | NOS3NOS1LMNAEPHX2ALDH1A1 | |
| SCHEMBL10452499 | 0.80 | ALDH1A1 (0.50) | NOS3NOS1LMNAEPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |