Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 11/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | HTT | P42858 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530442 | 1.00 | RECQL (0.56) | RECQLMAPTALDH1A1HTTGAA | |
| SCHEMBL899889 | 0.89 | MAPT (0.56) | RECQLMAPTALDH1A1HTTGAA | |
| SCHEMBL31531972 | 0.89 | MAPT (0.56) | RECQLMAPTALDH1A1HTTGAA | |
| SCHEMBL3162509 | 0.89 | MAPT (0.56) | RECQLMAPTALDH1A1HTTGAA | |
| Hydrochloric Acid SCHEMBL4078663 | 0.88 | MAPT (0.55) | RECQLMAPTALDH1A1HTTGAA | |
| SCHEMBL7366780 | 0.88 | MAPT (0.55) | RECQLMAPTALDH1A1HTTGAA | |
| SCHEMBL7366776 | 0.88 | MAPT (0.55) | RECQLMAPTALDH1A1HTTGAA | |
| Hydrochloric Acid SCHEMBL4071405 | 0.88 | MAPT (0.55) | RECQLMAPTALDH1A1HTTGAA | |
| SCHEMBL10729828 | 0.86 | RECQL (0.52) | RECQLMAPTALDH1A1HTTGAA | |
| SCHEMBL5797310 | 0.84 | MAPT (0.53) | RECQLMAPTALDH1A1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544886-A1 | METHOD OF EXTRACTING SENNOSIDES A, B and A1. | MADAUS AG (DE) | 1993-06-09 | — | — | EP | disclosed |
| US-4654347-A | USEFUL AS ANXIOLYTIC AND ANTIEPILEPTIC AGENTS, SEDATIVE-HYPNOTIC AGENTS AND SKELETAL MUSCLE RELAXANTS | AMERICAN CYANAMID COMPANY (US) | 1987-03-31 | — | — | US | disclosed |
| EP-0208846-A1 | [7-(3-Disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidines | AMERICAN CYANAMID COMPANY (US) | 1987-01-21 | — | — | EP | disclosed |