SCHEMBL9529289

SCHEMBL9529289

CCC(O)CCCC(C)(C)C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACACB O00763 1/20 0.71
ACACA Q13085 1/20 0.71
ACLY P53396 1/20 0.47
GPR84 Q9NQS5 4/20 0.38
CA2 P00918 1/20 0.38
MAPK1 P28482 1/20 0.38
FFAR4 Q5NUL3 1/20 0.37
FFAR1 O14842 1/20 0.37
PPARA Q07869 4/20 0.37
TBXAS1 P24557 2/20 0.36
TTR P02766 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C8 P10632 1/20 0.35
CHRM1 P11229 1/20 0.35
CYP2C9 P11712 1/20 0.35
TSHR P16473 1/20 0.35
ADRA1A P35348 1/20 0.35
PPARG P37231 1/20 0.35
HTR2B P41595 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7048284 0.89 ACACB (0.57) ACACBACACAACLYGPR84CA2
SCHEMBL12094483 0.89 ACACB (0.88) ACACBACACAACLYGPR84FFAR4
SCHEMBL3748635 0.89 ACACB (0.88) ACACBACACAACLYGPR84FFAR4
SCHEMBL3751463 0.87 ACACB (0.84) ACACBACACAACLYGPR84FFAR4
SCHEMBL205270 0.85 ACACB (0.96) ACACBACACAACLYGPR84FFAR4
SCHEMBL186486 0.85 ACACB (0.96) ACACBACACAACLYGPR84FFAR4
SCHEMBL23348922 0.83 ACACB (1.00) ACACBACACAACLYGPR84FFAR4
SCHEMBL186052 0.83 ACACB (1.00) ACACBACACAACLYGPR84FFAR4
SCHEMBL2737115 0.83 ACACB (0.78) ACACBACACAACLYGPR84FFAR4
Bempedoic Acid SCHEMBL185768 0.83 ACACB (1.00) ACACBACACAACLYGPR84FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0539541-A1 BIODEGRADABLE POLYMERIC COMPOSITIONS BASED ON STARCH AND THERMOPLASTIC POLYMERS. NOVAMONT SPA (IT) 1993-05-05 EP claimed
CN-1451027-A Thermoplastic starch compositions in corporating a particulate filler component KHASHOGGI E IND (US) 2003-10-22 CN disclosed
EP-0539541-A1 BIODEGRADABLE POLYMERIC COMPOSITIONS BASED ON STARCH AND THERMOPLASTIC POLYMERS. NOVAMONT SPA (IT) 1993-05-05 EP disclosed