Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315210 | 0.88 | KDM4E (0.60) | KCNH2HRH3ALDH1A1KDM4ETMEM97 | |
| Hydrochloric Acid SCHEMBL7322523 | 0.87 | KDM4E (0.59) | KCNH2HRH3ALDH1A1KDM4ETMEM97 | |
| SCHEMBL7316924 | 0.86 | HRH1 (0.61) | KCNH2HRH3DRD4DRD2MEN1 | |
| Hydrochloric Acid SCHEMBL9528358 | 0.85 | HRH1 (0.60) | KCNH2HRH3DRD4DRD2MEN1 | |
| SCHEMBL7327234 | 0.85 | ALDH1A1 (0.61) | KCNH2HRH3ALDH1A1KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9532204 | 0.84 | ALDH1A1 (0.60) | KCNH2HRH3ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL7321621 | 0.83 | KDM4E (0.59) | KCNH2HRH3ALDH1A1KDM4EDRD2 | |
| Hydrochloric Acid SCHEMBL7327685 | 0.83 | HRH3 (0.60) | KCNH2HRH3ALDH1A1KDM4ETMEM97 | |
| SCHEMBL7322566 | 0.83 | TMEM97 (0.61) | KCNH2HRH3TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9528868 | 0.82 | KDM4E (0.57) | KCNH2HRH3ALDH1A1KDM4EDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542846-A1 | N-HYDROCARBYL-4-SUBSTITUTED PIPERIDINES, THEIR PREPARATION AND USE AS CALCIUM BLOCKING AGENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-05-26 | — | — | EP | claimed |