Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.56 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528227 | 1.00 | HRH3 (0.56) | HRH3NOTUMDRD4ALDH1A1PDK1 | |
| SCHEMBL10628343 | 0.87 | PDK1 (0.45) | HRH3NOTUMALDH1A1PDK1 | |
| SCHEMBL10628341 | 0.87 | PDK1 (0.45) | HRH3NOTUMALDH1A1PDK1 | |
| SCHEMBL9527697 | 0.85 | HRH3 (0.61) | HRH3DRD4PDK1 | |
| SCHEMBL9527692 | 0.85 | HRH3 (0.61) | HRH3DRD4PDK1 | |
| SCHEMBL10634418 | 0.85 | HRH3 (0.61) | HRH3DRD4 | |
| SCHEMBL10634404 | 0.85 | HRH3 (0.61) | HRH3DRD4 | |
| SCHEMBL10631542 | 0.83 | DRD4 (0.41) | DRD4 | |
| SCHEMBL10634373 | 0.83 | DRD4 (0.59) | DRD4 | |
| SCHEMBL10634378 | 0.83 | DRD4 (0.59) | DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0286495-B1 | MORPHOLINE DERIVATIVES, THEIR PROCESS OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1993-05-12 | — | — | EP | claimed |
| US-4782054-A | ANTIISCHEMIC, ANTIHYPOXIC, STIMULANTS | ADIR ET COMPAGNIE (FR) | 1988-11-01 | — | — | US | disclosed |